NTRK1 Antibody| F40240-0.08ML/F40240-0.4ML

NTRK1 Antibody| F40240-0.08ML/F40240-0.4ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Format: Purified

Clone: 185CT47.6.1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1, k

Species Reactivity: Mouse

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:100-1:500

Application Note: Titration of the NTRK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This NTRK1 antibody is available for research use only.

Purity: Purified

Immunogen: This NTRK1 antibody was produced from a mouse immunized with NTRK1 recombinant protein.

Storage: Aliquot the NTRK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A