NVP-BEP800 | B2198

NVP-BEP800 is a potent oral inhibitor of Hsp90β (IC₅₀ = 58 nM). Displays strong anti-proliferative activity against various tumor cell lines and primary tumors in vitro and in vivo at well-tolerated doses.

NVP-BEP800 is a potent oral inhibitor of Hsp90β (IC₅₀ = 58 nM). Displays strong anti-proliferative activity against various tumor cell lines and primary tumors in vitro and in vivo at well-tolerated doses.

B2198 | NVP-BEP800 DataSheet

Alternate Name/Synonyms: 2-amino-4-[2,4-dichloro-5-[2-(1-pyrrolidinyl)ethoxy]phenyl]-N-ethyl-thieno[2,3-d]pyrimidine-6-carboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 847559-80-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₃Cl₂N₅O₂S

Molecular Weight: 480.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: EtOH (~5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent oral inhibitor of Hsp90β

MDL Number: N/A

PubChem CID: 25210273

SMILES: CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4

InChi: InChI=1S/C21H23Cl2N5O2S/c1-2-25-19(29)17-10-13-18(26-21(24)27-20(13)31-17)12-9-16(15(23)11-14(12)22)30-8-7-28-5-3-4-6-28/h9-11H,2-8H2,1H3,(H,25,29)(H2,24,26,27)

InChi Key: WJUNQSYQHHIVFX-UHFFFAOYSA-N