26
NVP-BSK805 dihydrochloride | B2200
- SKU:
- 26-B2200-GEN
- Availability:
- Usually shipped in 5 working days
Description
NVP-BSK805 is a potent and selective ATP-competitive inhibitor of JAK2 (IC₅₀ = 0.5 nM,). It displays >20-fold selectivity towards JAK1, JAK3 and TYK2.
NVP-BSK805 is a potent and selective ATP-competitive inhibitor of JAK2 (IC₅₀ = 0.5 nM,). It displays >20-fold selectivity towards JAK1, JAK3 and TYK2.
B2200 | NVP-BSK805 dihydrochloride DataSheet
Alternate Name/Synonyms: 4-(2,6-difluoro-4-(3-(1-(pip4-(2,6-difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine, dihydrochloride
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1942919-79-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₇H₂₈F₂N₆O • 2HCl
Molecular Weight: 563.5
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective ATP-competitive JAK2 inhibitor
MDL Number: N/A
PubChem CID: 57339395
SMILES: C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl
InChi: InChI=1S/C27H28F2N6O.2ClH/c28-23-12-18(13-24(29)22(23)17-34-8-10-36-11-9-34)21-2-1-3-25-27(21)33-26(15-31-25)19-14-32-35(16-19)20-4-6-30-7-5-20;;/h1-3,12-16,20,30H,4-11,17H2;2*1H
InChi Key: NUOCAPALWRHKCU-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |