OAC3 | B2828

OAC3 (Oct4-activating compound3) is an activator of octamer-binding transcription factor 4 (Oct4). Oct4 is an important regulator of embryonic stem cells pluripotency. It is used to generate induced pluripotent stem cells (iPSCs) with the transcription factors Sox2, Klf4, and c-Myc as a quartet. OAC3 at a concentration of 1 μM enhances reprogramming efficiency of mouse embryonic fibroblasts and generation of iPSC colonies.

OAC3 (Oct4-activating compound3) is an activator of octamer-binding transcription factor 4 (Oct4). Oct4 is an important regulator of embryonic stem cells pluripotency. It is used to generate induced pluripotent stem cells (iPSCs) with the transcription factors Sox2, Klf4, and c-Myc as a quartet. OAC3 at a concentration of 1 μM enhances reprogramming efficiency of mouse embryonic fibroblasts and generation of iPSC colonies.

B2828 | OAC3 DataSheet

Alternate Name/Synonyms: 4-fluoro-N-(1H-indol-5-yl)benzamide; N-(4-fluorobenzoyl)-5-amino-1H-indole

Appearance: Crystalline solid

Formulation:

CAS Number: 182564-41-6

Structure Available?: True

Peptide sequence:

Salt Form: False

Molecular Formula: C₁₅H₁₁FN₂O

Molecular Weight: 254.26

Cell-Permeable?: True

Purity: ≥98%

Solubilities: ~20 mg/ml in DMF in 0, ~12.5 mg/ml in in Ethanol, ~16 mg/ml in in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An activator of octamer-binding transcription factor 4

MDL Number:

PubChem CID: 2814506

SMILES: C1=CC(=CC=C1C(=O)NC2=CC3=C(C=C2)NC=C3)F

InChi: InChI=1S/C15H11FN2O/c16-12-3-1-10(2-4-12)15(19)18-13-5-6-14-11(9-13)7-8-17-14/h1-9,17H,(H,18,19)

InChi Key: RQJUZWRDCVBOMH-UHFFFAOYSA-N