OG-L002 | 9406

OG-L002 is a potent and specific inhibitor of Lysine Specific Demethylase-1(LSD-1) (IC₅₀ of 20 nM). Displays 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. It potently represses herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency. OG-L002 suppresses primary lytic infection of HSV in vivo in a mouse model.

OG-L002 is a potent and specific inhibitor of Lysine Specific Demethylase-1(LSD-1) (IC₅₀ of 20 nM). Displays 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. It potently represses herpes simplex virus (HSV) IE gene expression, genome replication, and reactivation from latency.

9406 | OG-L002 DataSheet

Alternate Name/Synonyms: 4'-((1S,2R)-2-aminocyclopropyl)-[1,1'-biphenyl]-3-ol

Appearance: White solid

Formulation: N/A

CAS Number: 1357302-64-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₅NO

Molecular Weight: 225.29

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and specific inhibitor of Lysine Specific Demethylase-1(LSD-1)

MDL Number: N/A

PubChem CID: 56639570

SMILES: C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O

InChi: InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1

InChi Key: DSOJSZXQRJGBCW-CABCVRRESA-N