26
Otenabant Hydrochloride | B3117
- SKU:
- 26-B3117-GEN
- Availability:
- Usually shipped in 5 working days
Description
Otenabant is a novel cannabinoid type 1 (CB1) receptor antagonist. It is effective at subnanomolar concentrations at human CB1 receptors in binding and functional assays, with Ki values of 0.7 nM and 0.12 nM respectively. It reverses cannabinoid agonist-induced responses, reduces food intake, and increases energy expenditure and oxidation of fat in rodent models.
Otenabant is a novel cannabinoid type 1 (CB1) receptor antagonist. It is effective at subnanomolar concentrations at human CB1 receptors in binding and functional assays, with Ki values of 0.7 nM and 0.12 nM respectively. It reverses cannabinoid agonist-induced responses, reduces food intake, and increases energy expenditure and oxidation of fat in rodent models.
B3117 | Otenabant Hydrochloride DataSheet
Alternate Name/Synonyms: CP-945598 HCl; CP-945,598; 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide;hydrochloride; 1-[9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic acid amide hydrochloride
Appearance: White to off-white solid powder
Formulation:
CAS Number: 686347-12-6
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₂₅H₂₆Cl₃N₇O
Molecular Weight: 546.88
Cell-Permeable?: True
Purity: ≥ 98%
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A novel CB1 receptor antagonist
MDL Number: MFCD18251544
PubChem CID: 16223963
SMILES: CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N.Cl
InChi: InChI=1S/C25H25Cl2N7O.ClH/c1-2-31-25(24(28)35)11-13-33(14-12-25)22-20-23(30-15-29-22)34(17-9-7-16(26)8-10-17)21(32-20)18-5-3-4-6-19(18)27;/h3-10,15,31H,2,11-14H2,1H3,(H2,28,35);1H
InChi Key: KPYUQCJBZGQHPL-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |