P529 | 2462

A potent PI3K/Akt/mTOR inhibitor that inhibits the TORC1 and TORC2 complexes. Displays inhibition of both Akt signaling and mTOR signaling similarly in tumor and vasculature. P529 inhibits tumor growth, angiogenesis and vascular permeability.

P529 is a potent PI3K/Akt/mTOR inhibitor that inhibits the TORC1 and TORC2 complexes.

2462 | P529 DataSheet

Alternate Name/Synonyms: 3-(4-methoxybenzyloxy)-8-(1-hydroxyethyl)-2-methoxy-6H-benzo[c]chromen-6-one ; Palomid 529

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 914913-88-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₂O₆

Molecular Weight: 406.43

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 40 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent PI3K/Akt/mTOR inhibitor

MDL Number: N/A

PubChem CID: 11998575

SMILES: CC(C1=CC2=C(C=C1)C3=CC(=C(C=C3OC2=O)OCC4=CC=C(C=C4)OC)OC)O

InChi: InChI=1S/C24H22O6/c1-14(25)16-6-9-18-19-11-22(28-3)23(12-21(19)30-24(26)20(18)10-16)29-13-15-4-7-17(27-2)8-5-15/h4-12,14,25H,13H2,1-3H3

InChi Key: YEAHTLOYHVWAKW-UHFFFAOYSA-N