Description
PIM2 Polyclonal Antibody | E-AB-10916 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: OTTHUMP00000025825, Pim 2 oncogene, Pim 2h, Pim-2h, PIM2, PIM2 Oncogene, PIM2, Pim2h, Proto Oncogene PIM2, Proto-oncogene Pim-2 (serine threonine kinase), Serine/threonine kinase PIM2, Serine/threonine-protein kinase Pim-2
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal Transduction
Background: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PIM2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A