Description
Pinacidil is a cyanoguanidine compound that acts as a potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively. Induces relaxation of serotonin-produced contractions in porcine and human arterial rings. Vasodilator. Antihypertensive agent.
Pinacidil is a cyanoguanidine compound that acts as a potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively. Induces relaxation of serotonin-produced contractions in porcine and human arterial rings. Vasodilator. Antihypertensive agent.
B1904 | Pinacidil monohydrate DataSheet
Alternate Name/Synonyms: (±)-N-Cyano-N′-4-pyridinyl-N″-(1,2,2-trimethylpropyl)guanidine monohydrate
Appearance: White solid
Formulation: N/A
CAS Number: 85371-64-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₁₉N₅ · H₂O
Molecular Weight: 263.34
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 15 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potassium channel opener
MDL Number: MFCD00242745
PubChem CID: 55329
SMILES: CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1.O
InChi: InChI=1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2
InChi Key: AFJCNBBHEVLGCZ-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |