Pinacidil monohydrate | B1904

Pinacidil is a cyanoguanidine compound that acts as a potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively. Induces relaxation of serotonin-produced contractions in porcine and human arterial rings. Vasodilator. Antihypertensive agent.

Pinacidil is a cyanoguanidine compound that acts as a potassium channel opener, activating the ATP-modulated potassium channels of guinea pig bladder and heart with Ki values of 104 and 251 nM, respectively. Induces relaxation of serotonin-produced contractions in porcine and human arterial rings. Vasodilator. Antihypertensive agent.

B1904 | Pinacidil monohydrate DataSheet

Alternate Name/Synonyms: (±)-N-Cyano-N′-4-pyridinyl-N″-(1,2,2-trimethylpropyl)guanidine monohydrate

Appearance: White solid

Formulation: N/A

CAS Number: 85371-64-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₁₉N₅ · H₂O

Molecular Weight: 263.34

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 15 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potassium channel opener

MDL Number: MFCD00242745

PubChem CID: 55329

SMILES: CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1.O

InChi: InChI=1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2

InChi Key: AFJCNBBHEVLGCZ-UHFFFAOYSA-N