PRDX2 Antibody | XW-7715

PRDX2 Antibody | XW-7715 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: 60-190

Research Area: Other

Tested Application: WB

Application: Peroxiredoxin-2 antibody can be used for the detection of Peroxiredoxin-2 by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 21.8 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: PRDX2 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: NKEFB, TDPX1, Peroxiredoxin-2, Natural killer cell-enhancing factor B, NKEF-B, PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, HEL-S-2a, Peroxiredoxin2, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, NKEF

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Enhances natural killer (NK) cells activity.

CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H₂O + ROH.

SUBUNIT: Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration.

SIMILARITY: Belongs to the ahpC/TSA family.

SUBCELLULAR LOCATION: Cytoplasm.

MISCELLANEOUS: The active site is the redox-active Cys-50 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-171-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.