Description
PRDX2 Antibody | XW-7715 | Gentaur UK, US & Europe Distribution
Host: Chicken
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: 60-190
Research Area: Other
Tested Application: WB
Application: Peroxiredoxin-2 antibody can be used for the detection of Peroxiredoxin-2 by Western Blot.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 21.8 kDa (calculated)
Validation: N/A
Isoform: N/A
Purification: Immunoaffinity Purified
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Condition: PRDX2 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: NKEFB, TDPX1, Peroxiredoxin-2, Natural killer cell-enhancing factor B, NKEF-B, PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, HEL-S-2a, Peroxiredoxin2, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, NKEF
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FUNCTION: Enhances natural killer (NK) cells activity.
CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
SUBUNIT: Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration.
SIMILARITY: Belongs to the ahpC/TSA family.
SUBCELLULAR LOCATION: Cytoplasm.
MISCELLANEOUS: The active site is the redox-active Cys-50 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-171-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.