PSMC2 Polyclonal Antibody | E-AB-11408

PSMC2 Polyclonal Antibody | E-AB-11408 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 26S protease complex, 26S protease regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, mammalian suppressor of sgv-1 of yeast, MSS1, Nbla10058, protease 26S subunit 7, proteasome 26S ATPase subunit 2, Proteasome 26S subunit ATPase 2, Proteasome 26S subunit ATPase 2, Protein MSS1, PRS7, PSMC2, putative protein product of Nbla10058, S7

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human PSMC2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 49 kDa

Molecular Weight(Observed): N/A