Description
PSMC2 Polyclonal Antibody | E-AB-11408 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: 26S protease complex, 26S protease regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, mammalian suppressor of sgv-1 of yeast, MSS1, Nbla10058, protease 26S subunit 7, proteasome 26S ATPase subunit 2, Proteasome 26S subunit ATPase 2, Proteasome 26S subunit ATPase 2, Protein MSS1, PRS7, PSMC2, putative protein product of Nbla10058, S7
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PSMC2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 49 kDa
Molecular Weight(Observed): N/A