PYGL Polyclonal Antibody | E-AB-11510

PYGL Polyclonal Antibody | E-AB-11510 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Glycogen phosphorylase, Glycogen phosphorylase L, Glycogen phosphorylase liver, Glycogen phosphorylase liver form, GSD6, Hers disease, glycogen storage disease type VI, liver form, OTTHUMP00000233649, OTTHUMP00000233651, Phosphorylase glycogen liver, Pygl, PYGL

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction

Background: This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1, 4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human PYGL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 97 kDa

Molecular Weight(Observed): N/A