Description
PYGL Polyclonal Antibody | E-AB-11510 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Glycogen phosphorylase, Glycogen phosphorylase L, Glycogen phosphorylase liver, Glycogen phosphorylase liver form, GSD6, Hers disease, glycogen storage disease type VI, liver form, OTTHUMP00000233649, OTTHUMP00000233651, Phosphorylase glycogen liver, Pygl, PYGL
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction
Background: This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1, 4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PYGL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:30-1:150
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 97 kDa
Molecular Weight(Observed): N/A