Description
QDPR Polyclonal Antibody | E-AB-52713 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: 6, 7 dihydropteridine reductase, DHPR, DHPR, Dihydropteridine reductase, HDHPR, HPR, PKU2, Qdpr, Quinoid dihydropteridine reductase, SDR33C1, Short chain dehydrogenase/reductase family 33C, member 1
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Metabolism, Signal transduction
Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Concentration: 1.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human QDPR
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 26 kDa
Molecular Weight(Observed): Refer to figures