QDPR Polyclonal Antibody | E-AB-52713

QDPR Polyclonal Antibody | E-AB-52713 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 6, 7 dihydropteridine reductase, DHPR, DHPR, Dihydropteridine reductase, HDHPR, HPR, PKU2, Qdpr, Quinoid dihydropteridine reductase, SDR33C1, Short chain dehydrogenase/reductase family 33C, member 1

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signal transduction

Background: This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Concentration: 1.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human QDPR

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 26 kDa

Molecular Weight(Observed): Refer to figures