(R,S)-Lenalidomide | 1862

Cell-permeable. An analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor-α (TNF-α). Displays potent anti-tumor and anti-inflammatory effects as well as modulates and potentiates host immune responses against multiple myeloma.

(R,S)-Lenalidomide is an analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor-α (TNF-α).

1862 | (R,S)-Lenalidomide DataSheet

Alternate Name/Synonyms: (R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 191732-72-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₁₃N₃O₃

Molecular Weight: 259.26

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~100 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: Tumor Necrosis Factor-α (TNF-α) inhibitor

MDL Number: MFCD07772307

PubChem CID: 216326

SMILES: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N

InChi: InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)

InChi Key: GOTYRUGSSMKFNF-UHFFFAOYSA-N