Description
RAPGEF1 Polyclonal Antibody | E-AB-19964 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: C3G, C3G protein, CRK SH3 binding GNRP, CRK SH3-binding GNRP, DKFZp781P1719, GRF 2, GRF2, Guanine nucleotide releasing factor 2 (specific for crk proto oncogene), Guanine nucleotide releasing factor 2, Guanine nucleotide-releasing factor 2, OTTHUMP00000064558, Protein C3G, Rap guanine nucleotide exchange factor (GEF) 1, Rap guanine nucleotide exchange factor 1, RAPGEF 1, RAPGEF1, RPGF1
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal transduction
Background: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Concentration: 1.32 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human RAPGEF1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A