RAPGEF1 Polyclonal Antibody | E-AB-19964

RAPGEF1 Polyclonal Antibody | E-AB-19964 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C3G, C3G protein, CRK SH3 binding GNRP, CRK SH3-binding GNRP, DKFZp781P1719, GRF 2, GRF2, Guanine nucleotide releasing factor 2 (specific for crk proto oncogene), Guanine nucleotide releasing factor 2, Guanine nucleotide-releasing factor 2, OTTHUMP00000064558, Protein C3G, Rap guanine nucleotide exchange factor (GEF) 1, Rap guanine nucleotide exchange factor 1, RAPGEF 1, RAPGEF1, RPGF1

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal transduction

Background: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

Concentration: 1.32 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human RAPGEF1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A