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Raptor polyclonal Antibody | BS91154
- SKU:
- BW-BS91154
- Availability:
- Usually ships in 5 working days
Description
Raptor polyclonal Antibody | BS91154 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC IHC FC
Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Raptor polyclonal Antibody detects endogenous levels of Raptor protein.
Molecular Weight: 131 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Raptor, RPTOR, KIAA1303, RAPTOR, KIAA1303, KOG1, Mip1, P150 target of rapamycin (TOR) scaffold protein, p150 target of rapamycin (TOR) scaffold protein containing WD repeats, P150 target of rapamycin (TOR) -scaffold protein, Raptor, Regulatory associated protein of mTOR, Regulatory associated protein of MTOR complex 1, Regulatory-associated protein of mTOR, RPTOR, RPTOR,
Immunogen: Synthetic peptide within human Raptor aa 100-150.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified.
Pathway: