Raptor polyclonal Antibody | BS91154

Raptor polyclonal Antibody | BS91154 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Raptor polyclonal Antibody detects endogenous levels of Raptor protein.

Molecular Weight: 131 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Raptor, RPTOR, KIAA1303, RAPTOR, KIAA1303, KOG1, Mip1, P150 target of rapamycin (TOR) scaffold protein, p150 target of rapamycin (TOR) scaffold protein containing WD repeats, P150 target of rapamycin (TOR) -scaffold protein, Raptor, Regulatory associated protein of mTOR, Regulatory associated protein of MTOR complex 1, Regulatory-associated protein of mTOR, RPTOR, RPTOR,

Immunogen: Synthetic peptide within human Raptor aa 100-150.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: