RBPJ Antibody| F45603-0.08ML/F45603-0.4ML

RBPJ Antibody| F45603-0.08ML/F45603-0.4ML | Gentaur UK, US & Europe Distribution

Background: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, IF, ELISA

Application Details: Western blot: 1:1000-2000, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50

Application Note: Titration of the RBPJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This RBPJ antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.

Storage: Aliquot the RBPJ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A