REST Polyclonal Antibody | E-AB-17813

REST Polyclonal Antibody | E-AB-17813 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Neural Restrictive Silencer Factor, Neural-restrictive silencer factor, Neuron Restrictive Silencer Factor, NRSF, RE1 silencing transcription factor, RE1-silencing transcription factor, Repressor binding to the X2 box, rest, REST protein, REST, X2 box repressor, XBR

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Background: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human REST

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A