Description
REST Polyclonal Antibody | E-AB-17813 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Neural Restrictive Silencer Factor, Neural-restrictive silencer factor, Neuron Restrictive Silencer Factor, NRSF, RE1 silencing transcription factor, RE1-silencing transcription factor, Repressor binding to the X2 box, rest, REST protein, REST, X2 box repressor, XBR
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Background: This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human REST
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A