RG7834 | B2732

RG7834 is a highly selective and orally bioavailable HBV (Hepatitis B Virus) inhibitor, that potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC₅₀s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.

RG7834 is a highly selective and orally bioavailable HBV (Hepatitis B Virus) inhibitor, that potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC₅₀s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.

B2732 | RG7834 DataSheet

Alternate Name/Synonyms: RO7020322,(6S)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid,RG-7834

Appearance: White to off-white solid

Formulation:

CAS Number: 2072057-17-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₇NO₆

Molecular Weight: 401.46

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A highly selective and orally bioavailable HBV inhibitor

MDL Number:

PubChem CID: 118261815

SMILES: CC(C)C1CC2=CC(=C(C=C2C3=CC(=O)C(=CN13)C(=O)O)OC)OCCCOC

InChi: InChI=1S/C22H27NO6/c1-13(2)17-8-14-9-21(29-7-5-6-27-3)20(28-4)10-15(14)18-11-19(24)16(22(25)26)12-23(17)18/h9-13,17H,5-8H2,1-4H3,(H,25,26)/t17-/m0/s1

InChi Key: KBXLMOYQNDMHQT-KRWDZBQOSA-N