RHEB Antibody| F41677-0.08ML/F41677-0.4ML

RHEB Antibody| F41677-0.08ML/F41677-0.4ML | Gentaur UK, US & Europe Distribution

Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat, Bovine

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:50-1:100

Application Note: Titration of the RHEB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This RHEB antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 104-134 from the human protein was used as the immunogen for this RHEB antibody.

Storage: Aliquot the RHEB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A