RHOB Polyclonal Antibody | E-AB-12248

RHOB Polyclonal Antibody | E-AB-12248 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Aplysia RAS-related homolog 6, ARH6, ARHB, H6, MST081, MSTP081, oncogene RHO H6, ras homolog family member B, ras homolog gene family, member B, Rho cDNA clone 6, Rho related GTP binding protein RhoB Precursor, Rho-related GTP-binding protein RhoB, Rhob, RHOB, RHOH6

Application: WB, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction

Background: Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human RHOB

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 22 kDa

Molecular Weight(Observed): N/A