Description
RHOB Polyclonal Antibody | E-AB-12248 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Aplysia RAS-related homolog 6, ARH6, ARHB, H6, MST081, MSTP081, oncogene RHO H6, ras homolog family member B, ras homolog gene family, member B, Rho cDNA clone 6, Rho related GTP binding protein RhoB Precursor, Rho-related GTP-binding protein RhoB, Rhob, RHOB, RHOH6
Application: WB, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Signal Transduction
Background: Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human RHOB
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 22 kDa
Molecular Weight(Observed): N/A