RUNX3 Antibody| F44057-0.08ML/F44057-0.4ML/N1190-100UG/N1190-25UG

RUNX3 Antibody| F44057-0.08ML/F44057-0.4ML/N1190-100UG/N1190-25UG | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: IHC, IF, WB, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50

Application Note: Titration of the RUNX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This RUNX3 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody.

Storage: Aliquot the RUNX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A