RYR1 polyclonal Antibody | BS91190

RYR1 polyclonal Antibody | BS91190 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: DotBlot IHC FC

Application Range: DotBlot:1:500-1:1,000 IHC:1:50-1:200 FC:1:50-1:100

Background: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: RYR1 polyclonal Antibody detects endogenous levels of RYR1 protein.

Molecular Weight: 565 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RYR-1, RyR1, RYR1, RYDR, Arrhythmogenic right ventricular dysplasia 2, ARVC2, ARVD2, Brain ryanodine receptor calcium release channel, Brain type ryanodine receptor, Cardiac muscle ryanodine receptor calcium release channel, Cardiac muscle type ryanodine receptor, CCO, Central core disease of muscle, HBRR, hRYR 2, hRYR2, MHS, MHS1, Ryanodine receptor 1 (skeletal), Ryanodine receptor 1, Ryanodine receptor 2 (cardiac), Ryanodine receptor 2, Ryanodine receptor 3, Ryanodine receptor type1, RYDR, RYR 1, RYR 2, RYR 3, RYR, RYR-1, RyR1, RYR1, RYR2, RYR3, Sarcoplasmic reticulum calcium release channel, Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle type ryanodine receptor, Skeletal muscle-type ryanodine receptor, SKRR, Type 1 like ryanodine receptor, Type 1 ryanodine receptor, VTSIP,

Immunogen: Synthetic peptide within human RYR1 aa 1350-1400.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified.

Pathway: