SAFB2 polyclonal Antibody | BS70616

SAFB2 polyclonal Antibody | BS70616 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: SAF-B2 (scaffold attachment factor B2) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins) . SAF-B2, and the related SAF-B, bind to the estrogen receptor (ER) and are expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B and SAF-B2 may play a role in breast cancer by mediating cellular proliferation and division. Unlike SAF-B, which is exclusively nuclear, SAF-B2 is found in the cytoplasm as well as the nucleus.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SAFB2 polyclonal Antibody detects endogenous levels of SAFB2 protein.

Molecular Weight: ~ 160 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Scaffold attachment factor B2; SAF-B2; SAFB2; KIAA0138

Immunogen: Recombinant protein of human SAFB2.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: