BW
SAFB2 polyclonal Antibody | BS70616
- SKU:
- BW-BS70616
- Availability:
- Usually ships in 5 working days
Description
SAFB2 polyclonal Antibody | BS70616 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200
Background: SAF-B2 (scaffold attachment factor B2) is a nuclear matrix-associated protein that binds to matrix- or scaffold-associating regions (MARs or SARs) on DNA and interacts with RNA polymerase II and serine-/arginine-rich RNA processing factors (SR proteins) . SAF-B2, and the related SAF-B, bind to the estrogen receptor (ER) and are expressed in several breast cancer cell lines at varying levels. Subsequently, SAF-B and SAF-B2 may play a role in breast cancer by mediating cellular proliferation and division. Unlike SAF-B, which is exclusively nuclear, SAF-B2 is found in the cytoplasm as well as the nucleus.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: SAFB2 polyclonal Antibody detects endogenous levels of SAFB2 protein.
Molecular Weight: ~ 160 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Scaffold attachment factor B2; SAF-B2; SAFB2; KIAA0138
Immunogen: Recombinant protein of human SAFB2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: