Sarcoglycanγ polyclonal Antibody | BS91205

Sarcoglycanγ polyclonal Antibody | BS91205 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB IP IHC

Application Range: WB:1:500-1:2,000 IP:1:50-1:100 IHC:1:50-1:200

Background: The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Sarcoglycanγ polyclonal Antibody detects endogenous levels of Sarcoglycanγ protein.

Molecular Weight: 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Gamma-SG, 35DAG, SGCG, 35 kDa dystrophin associated glycoprotein, 35 kDa dystrophin-associated glycoprotein, 35DAG, 35kD dystrophin associated glycoprotein, 35kDa dystrophin-associated glycoprotein, A4, DAGA4, DMDA, DMDA1, Gamma SG, Gamma-sarcoglycan, Gamma-SG, LGMD2C, MAM, MGC130048, Sarcoglycan gamma, SCARMD2, SCG3, SGCG, SGCG, TYPE,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: