LBD
SCG3 Antibody (C-term) [AMR09825G]
- SKU:
- LBD-AMR09825G
- Availability:
- Usually ships in 5 working days
Description
SCG3 Antibody (C-term) [AMR09825G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SCG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the C-terminal region of human SCG3.
Cellular Localisation: Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P47868}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P47868}; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. {ECO:0000250|UniProtKB:P47868}
Molecular Weight: 53005
Clone: Polyclonal
Gene Name: SCG3
Gene ID: 29106
Function: Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:19357184) . Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity) . May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (PubMed:29154827) .
Summary: Tissue Location: Expressed in brain, heart, kidney, liver and skeletal muscle.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Secretogranin-3, Secretogranin III, SgIII, SCG3