Pifithrin-μ (PFT-μ) is an inhibitor of p53-mediated apoptosis, preventing p53 binding to Bcl-xL and Bcl-2 at the mitochondria without affecting p53 transactivational activities. In vitro, PFT-μ binds...
U-73122 is an Inhibitor of receptor-coupled phospholipase C-dependent processes in platelets and neutrophils via interfering with G protein-PLC interaction. A useful tool for probing the involvement...