SEMA3C Polyclonal Antibody | E-AB-65295

SEMA3C Polyclonal Antibody | E-AB-65295 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: SEMA3C, SEMAE, SemE

Application: WB, IF

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Neuroscience

Background: This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human SEMA3C (NP_006370.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000 IF 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 26 kDa/85 kDa

Molecular Weight(Observed): 85 kDa