Description
SEMA3C Polyclonal Antibody | E-AB-65295 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: SEMA3C, SEMAE, SemE
Application: WB, IF
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cardiovascular, Neuroscience
Background: This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human SEMA3C (NP_006370.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:200-1:2000 IF 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 26 kDa/85 kDa
Molecular Weight(Observed): 85 kDa