LBD
SFXN1 Antibody (C-term) [AMR09894G]
- SKU:
- LBD-AMR09894G
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Description
SFXN1 Antibody (C-term) [AMR09894G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SFXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-321 amino acids from the C-terminal region of human SFXN1.
Cellular Localisation: Mitochondrion inner membrane; Multi-pass membrane protein
Molecular Weight: 35619
Clone: Polyclonal
Gene Name: SFXN1 (HGNC:16085)
Gene ID: 94081
Function: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778) . Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778) . Transports both D-serine and L-serine (PubMed:30442778) . Also able to transport other amino-acids, such as alanine (PubMed:30442778) . May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity) .
Summary: Tissue Location: Highly expressed in tissues with high one-carbon metabolism activity, such as blood, liver and kidney
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Sideroflexin-1, Tricarboxylate carrier protein, TCC, SFXN1