LBD
SGF29 Antibody (C-term) [APR32132G]
- SKU:
- LBD-APR32132G
- Availability:
- Usually ships in 5 working days
Description
SGF29 Antibody (C-term) [APR32132G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This SGF29 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-208 amino acids from the C-terminal region of human SGF29.
Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:P0C606}.
Molecular Weight: 33238
Clone: Polyclonal
Gene Name: SGF29 (HGNC:25156)
Gene ID: 112869
Function: Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes (PubMed:19103755, PubMed:20850016, PubMed:26421618, PubMed:21685874, PubMed:26578293) . SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (PubMed:20850016, PubMed:26421618, PubMed:21685874, PubMed:26578293) . In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me (PubMed:20850016) . Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival (PubMed:23894581) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: SAGA-associated factor 29 homolog, Coiled-coil domain-containing protein 101, CCDC101, SGF29