SIRT2 Inhibitor | 1857

Brain- permeable. A potent and selective sirtuin 2 deacetylase (SIRT2) inhibitor. Reduces neuronal cholesterol by inhibiting SIRT2 activity.

SIRT2 inhibitor is a brain-permeable, potent and selective sirtuin 2 deacetylase (SIRT2) inhibitor. Reduces neuronal cholesterol by inhibiting SIRT2 activity.

1857 | SIRT2 Inhibitor DataSheet

Alternate Name/Synonyms: 3-(1-azepanylsulfonyl)-N-(3-bromphenyl)benzamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 420831-40-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₉H₂₁BrN₂O₃S

Molecular Weight: 437.35

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A brain-permeable SIRT2 inhibitor

MDL Number: MFCD03140195

PubChem CID: 1328033

SMILES: C1CCCN(CC1)S(=O)(=O)C2=CC=CC(=C2)C(=O)NC3=CC(=CC=C3)Br

InChi: InChI=1S/C19H21BrN2O3S/c20-16-8-6-9-17(14-16)21-19(23)15-7-5-10-18(13-15)26(24,25)22-11-3-1-2-4-12-22/h5-10,13-14H,1-4,11-12H2,(H,21,23)

InChi Key: IYAYHZZWYNXHEQ-UHFFFAOYSA-N