Description
SLIT2 Polyclonal Antibody | E-AB-13664 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: Drad 1, E030015M03Rik, E130320P19Rik, FLJ14420, OTTHUMP00000158695, OTTHUMP00000217852, OTTHUMP00000217853, OTTHUMP00000217854, Slil 3, Slil3, Slit 2, Slit homolog 2 (Drosophila), Slit homolog 2, Slit homolog 2 protein, Slit homolog 2 protein C-product, Slit-2, Slit2, SLIT2
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Neuroscience
Background: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.
Concentration: 0.3 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human SLIT2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 170 kDa
Molecular Weight(Observed): N/A