SLIT2 Polyclonal Antibody | E-AB-13664

SLIT2 Polyclonal Antibody | E-AB-13664 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Drad 1, E030015M03Rik, E130320P19Rik, FLJ14420, OTTHUMP00000158695, OTTHUMP00000217852, OTTHUMP00000217853, OTTHUMP00000217854, Slil 3, Slil3, Slit 2, Slit homolog 2 (Drosophila), Slit homolog 2, Slit homolog 2 protein, Slit homolog 2 protein C-product, Slit-2, Slit2, SLIT2

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience

Background: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human SLIT2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 170 kDa

Molecular Weight(Observed): N/A