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Sphingosine Kinase Inhibitor, SKI-II | 2047
- SKU:
- 26-2047-GEN
- Availability:
- Usually shipped in 5 working days
Description
Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3-kinase, or PKCα at concentrations up to 60 µM.
Sphingosine Kinase Inhibitor, SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3-kinase, or PKCα at concentrations up to 60 µM.
2047 | Sphingosine Kinase Inhibitor, SKI-II DataSheet
Alternate Name/Synonyms: 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol
Appearance: Off-white solid
Formulation: N/A
CAS Number: 312636-16-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₁ClN₂OS
Molecular Weight: 302.78
Cell-Permeable?: Yes
Purity: ≥90% by NMR
Solubilities: DMSO (100 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A non-lipid pan-sphingosine kinase (SK) inhibitor
MDL Number: MFCD00733553
PubChem CID: 753704
SMILES: C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13 (19)8-6-12/h1-9,19H,(H,17,18)
InChi Key: ZFGXZJKLOFCECI-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |