BW
STRAP polyclonal Antibody | BS70705
- SKU:
- BW-BS70705
- Availability:
- Usually ships in 5 working days
Description
STRAP polyclonal Antibody | BS70705 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IF
Application Range: WB 1:500 - 1:2000 IF 1:50 - 1:200
Background: STRAP, another antagonist to the TGFβ signalling pathway, specifically interacts with Smad7, but not Smad6, to synergistically block TGF∫-induced transcriptional activation. The gene encoding the human homolog of STRAP (as designated in mouse), called unr-interacting protein, maps to chromosome 12p12.3. Unr-interacting protein is 97% homologous to STRAP at the amino acid level. The unr-interacting protein binds unr, a cytoplasmic RNA-binding protein with five cold-shock domains that is involved in RNA translation. The presence of the STRAP gene in a variety of species from mammals to yeast, indicates that STRAP function is evolutionarily conserved in eukaryotic cells.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: STRAP polyclonal Antibody detects endogenous levels of STRAP protein.
Molecular Weight: ~ 38 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: MAWD; PT-WD; UNRIP;
Immunogen: Recombinant protein of human STRAP.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: