Description
SUN1 polyclonal Antibody | BS9956M | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Rat
Application: WB IHC ICC FC
Application Range: WB: 1:500-1:2000 IHC: 1:50-1:200 ICC: 1:50-1:200 FC: 1:50-1:100
Background: UNC84A (UNC84 homolog A), also known as SUN1, is a multi-pass nuclear membrane protein that is involved in nuclear anchoring and migration. Highly expressed in heart, brain and testis, UNC84A functions as an A-type Lamin-binding protein that forms a link between the inner and outer nuclear envelope membranes. This link acts as a structural bridge between the nuclear interior and the Actin cytoskeleton and is essential for proper localization of nuclear envelope proteins. Additionally, UNC84A may be involved in telomere attachment and in normal testis development. UNC84A contains one UNC84 (SUN) domain and exists as four isoforms due to alternative splicing events.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: This Antibody detects endogenous levels of SUN1 and does not cross-react with related proteins.
Molecular Weight: ~ 90 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: SUN domain-containing protein 1; Protein unc-84 homolog A; Sad1/unc-84 protein-like 1; SUN1; KIAA0810; UNC84A
Immunogen: Recombinant protein corresponding to C-terminal human SUN1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Protein A affinity purified.
Pathway: