SUN1 polyclonal Antibody | BS9956M

SUN1 polyclonal Antibody | BS9956M | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Rat

Application: WB IHC ICC FC

Application Range: WB: 1:500-1:2000 IHC: 1:50-1:200 ICC: 1:50-1:200 FC: 1:50-1:100

Background: UNC84A (UNC84 homolog A), also known as SUN1, is a multi-pass nuclear membrane protein that is involved in nuclear anchoring and migration. Highly expressed in heart, brain and testis, UNC84A functions as an A-type Lamin-binding protein that forms a link between the inner and outer nuclear envelope membranes. This link acts as a structural bridge between the nuclear interior and the Actin cytoskeleton and is essential for proper localization of nuclear envelope proteins. Additionally, UNC84A may be involved in telomere attachment and in normal testis development. UNC84A contains one UNC84 (SUN) domain and exists as four isoforms due to alternative splicing events.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of SUN1 and does not cross-react with related proteins.

Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: SUN domain-containing protein 1; Protein unc-84 homolog A; Sad1/unc-84 protein-like 1; SUN1; KIAA0810; UNC84A

Immunogen: Recombinant protein corresponding to C-terminal human SUN1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified.

Pathway: