This liposome product has a small mean particles size of about 80-90 nm and a lipid composition comparable to that for the commercial Doxil. It can be used for active loading of weakly basic compunds.

Specificity:

• • Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)
  • Mean particle size: 85 nm (80 – 90nm)
  • Lipid concentration: 60mM (60 – 70 mM)
  • Hydration buffer (loading battery): 250 mM ammonium sulfate
  • External solution: 10% sucrose, 20mM NaPO4, pH 6.5 ± 0.2

Applications:

• It can be used for active loading of weakly basic compunds.

Storage conditions:

• 2-8 °C, do not freeze

Shelf life:

• 6 months.