TGFB1 Antibody (N-term) [APR07196G]

TGFB1 Antibody (N-term) [APR07196G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-50 amino acids of human TGFB1.

Cellular Localisation: [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix

Molecular Weight: 44341

Clone: Polyclonal

Gene Name: TGFB1 (HGNC:11766)

Gene ID: 7040

Function: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.

Summary: Tissue Location: Highly expressed in bone (PubMed:11746498, PubMed:17827158) . Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158) . Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Transforming growth factor beta-1, TGF-beta-1, Latency-associated peptide, LAP, TGFB1, TGFB